Hugo        AllelePos a.a.Pos Residue   Variant   Freq      PPHpredict              SIFTpredict   
CYP4B1      013611    111     A         V         0.01      benign                  TOLERATED     
CYP4B1      015965    173     R         W         0.14      benign                  INTOLERANT    
CYP4B1      016688    264     R         W         0.01      probably damaging       INTOLERANT    
CYP4B1      016719    274     R         Q         0.01      benign                  TOLERATED     
CYP4B1      017626    322     S         G         0.01      benign                  INTOLERANT    
CYP4B1      017648    329     Y         S         0.03      possibly damaging       INTOLERANT    
CYP4B1      017655    331     M         I         0.34      benign                  INTOLERANT    
CYP4B1      017680    340     R         C         0.21      probably damaging       INTOLERANT    
CYP4B1      017723    354     F         C         0.03      benign                  INTOLERANT    
CYP4B1      019568    375     R         C         0.23      probably damaging       INTOLERANT    
CYP4B1      021191    482     R         Q         0.02      possibly damaging       INTOLERANT