9:00 - 9:30

Introduction: NIEHS SNPs Workshop and the Environmental Genome Project (Debbie Nickerson)

9:30 - 10:30

SNP Resources (Mark Rieder)

Brief Review of SNP Discovery Methods
SNP Databases
Candidate Gene (NIEHS-oriented)

10:30 - 10:45

Break

10:45 - 12:00

SNP Resources (Debbie Nickerson)

NIEHS SNPs
NIEHS Gene Resource Tools
NCBI SNP Resources

12:00 - 1:30

Lunch

1:30 - 3:00

Interactive Tutorial 1: Using NIEHS Database Resources (All)

GeneSNPs
NIEHS SNPs
dbSNP and Entrez SNP
SIFT
PolyPhen
PolyDom

3:00 - 3:15

Break

3:15 - 4:15

SNP Selection (Dana Crawford)

Linkage Disequilibrium
Haplotype Inference
Haplotype Tagging
SNP/Haplotype Selection Methods

9:00 - 10:30

Interactive Tutorial 2: Web Tools for SNP Selection (All)

EGP - GVS
Linkage Disequilibrium
Haplotype Analysis
Site Selection

10:30 - 10:45

Break

10:45 - 12:15

SNP Genotyping (Debbie Nickerson)

Technology Platforms
Candidate Gene
Whole Genome
Data Quality Control

12:15 - 1:45

Lunch

1:45 - 3:30

Association Analysis (Dana Crawford)

Study Design
Haplotype Analysis vs. SNP Analysis
Analysis Methods
Candidate Gene
Whole Genome
Replication and Function

3:30 - 3:45

Break

3:45 - 4:30

Medical Resequencing: Future Innovations and Sequence-Based Association Analysis (Mark Rieder)

Genotype-Based Warfarin Dose Prediction